Agreed, at least in principle. It's the best sounding out of all of them by far.
But.. It's way complicated. That's actually the biggest gripe I've had as well, that there's just too much stuff to mess with and you end up going down rabbit holes easily and you lose your ear for what you wanted to begin with. At first I LOVED that it was so tweakable, but then I kept finding myself tweaking.. And tweaking.. And tweaking.. And tweaking.. Only to find that I strayed so far from what I intended that I'd lose the inspiration that I originally had.
However, you can actually get tones that none of the others can do because of it, so it's a big toss up.
Buuut.. As he mentions, the stock profiles are great so you don't actually have to go and tweak all the little details if you don't want to, so perhaps the "it's too tweakable for it's own good" isn't really a great complaint. You can dial up an amp and a cab and tweak the EQ a bit and leave it at that without messing with tube biasing and such.
He's right about the GUI though. It's the kind of GUI that a software engineer would develop, not the kind of GUI that an actual GUI designer would produce.
I picked one of these up a while back, but I ended up moving it shortly after. I probably didn't give it the chance it deserved. I just felt overwhelmed every time I turned it on. I never felt inspired to play. It always seemed like a chore. I'd just rather twist some amp and pedal knobs, so I went the route of the Suhr IR RL. I have no idea if it sounds better or worse than the Axe.
I used the Axe2 and knew it like the back of my hand, front panel or Editor. Then I got the 3 and I struggle a bit with the front panel, always grabbing a wrong knob or something. So yes, there's some merit to the complexity. However, biggest reason I get lost into the front panel editing is I don't ever need to tweak it! So I haven't needed to learn it. I can see how totally frustrating it could be for someone who isn't an audio nerd and doesn't understand anything the unit is doing. Giving it chaff because the deeeeepest amp parameters exist and are exposed to the user is a bit silly though. Just don't touch em. If a modeler sounds like plastic barbie doll wrapped in mud, I don't care if it has handsfree thought reading brain wave analyzer as UI.
I wouldn't be terribly surprised if Axe4 had an Apple style UI with all the deep parameters removed. On the other hand it also seems Cliff wants to keep the nerdability and won't dumb it down. Perhaps a switch between basic and deep modes or something.